Bonegraft

16.09.2025

Effect of Cold Atmospheric Plasma on Cell Adhesion in Dental Implants

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Influence of cold atmospheric plasma on dental implant materials an in vitro analysis



Effect of Cold Atmospheric Plasma on Cell Adhesion in Dental Implants

Next-generation plasma technologies have the potential to accelerate biological processes that support osseointegration on dental implant surfaces.
Cold Atmospheric Plasma (CAP) enhances the wettability and biocompatible energy of implant surfaces, facilitating stronger cell adhesion. Research indicates that short-term CAP exposure on titanium and zirconia discs can increase osteoblast activity and improve overall surface energy.

Research Findings
✅ CAP application preserved the elemental balance of the surface while improving wettability.
✅ Exposure times of 60–120 seconds significantly enhanced cell proliferation.
✅ Biological response was notably increased in MG-63 osteoblast-like cells and HGF-1 gingival fibroblasts.

Clinical Potential
These results suggest that CAP may be effectively used for surface activation prior to implant placement or to support re-osseointegration after peri-implantitis treatment.
Conclusion
Plasma-assisted surface modification, when combined with Powerbone’s SLA Active Surface technology, represents a major advancement toward achieving faster and more reliable bone-implant integration.

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