Bonegraft

Atmospheric Plasma Enhances Wettability and Cell Spreading on Dental Implant Metals

A research team from the University of Greifswald demonstrated that Cold Atmospheric Plasma (CAP) significantly improves surface wettability and osteoblastic cell spreading on titanium implants with various surface topographies.

Exposure to argon plasma for 60–120 seconds reduced the water contact angle to nearly 0°, turning the surfaces ultra-hydrophilic and increasing cell area by over 57%.

CAP treatment also showed potential for supporting re-osseointegration after peri-implantitis therapy without affecting metabolic cell activity.

✅ Plasma made titanium surfaces ultra-hydrophilic, independent of roughness.

✅ Osteoblast-like cells (MG-63) exhibited enhanced spreading and surface adaptation.

✅ No inhibitory effect on metabolic activity observed.

✅ CAP may support re-osseointegration after biofilm removal.

Atmospheric plasma represents a safe and effective surface modification method, promoting stronger cell adhesion and improved osseointegration performance in dental implants.